Funny I originally used ‘must make’ because it added urgency but then changed it. So I guess I finally nailed that logline:

A?Bioweapons Collector must make the hazardous journey through?sacred caverns of the ?Land of the Souls?to prevent ?a pandemic ?from the ?virus he created.

and just in case that didn’t work I also decided this is fine:

When a bioweapons collector resurrects a deadly virus, he must seek the aid of a shaman to find a cure before it creates a pandemic.

I have also been researching high concept ideas and sure that isn’t for the writer to decide but I do wonder if the high concept question can be raised in the query. Here is what I believe is my high concept question:

What if scientists were able to resurrect an ancient virus and it escaped the lab during testing.

That is the very premise of my story that is loosely based on an actual account. Are you allowed to posit questions like this in query letters?

I read this and it is correct. I worked with DNA for nearly 20 years and all life is created by 4 simple compounds that are represented by A, C, T, G ?in DNA. ?My story has to do the same. ?I really liked this article.
Screenwriting guru Blake Snyder has often referred to the log line as the DNA of your film, and I believe that statement to be very true.
http://www.indiewire.com/2014/01/how-to-write-the-perfect-logline-and-why-its-as-important-as-your-screenplay-31710/

A- antagonist
C- main Character
T- time or when
G- Goal

A?Bioweapons Collector makes the hazardous journey through?sacred caverns of the ?Land of the Souls?to prevent ?a pandemic ?from the ?virus he created.

This is simple and direct, it has the
protagonist- bioweapons collector= C
when- after the virus he created= T
Goal- to??prevent a pandemic-=G
antagonist- its the virus, antagonists don’t have to be human, they simply oppose the goal of the protagonist= A

hook- a bad ass seeks redemption for the evil he caused by going on a dangerous pilgrimage. ?All done with only 25 words ;