When he is framed for the murder of his boss, a genetically engineered assassin must protect the boss’s daughter from his enemies to clear his name after he is hunted by three major Syndicates.

Remove ?makes it personal? and describe the story, rather set out to clear his name.

Captures and tortures likely suspects to...
Decides to kill his bosses enemies to ....

The guy's an assassin.? Why should I emphasize with his plight?? Why should I want to root for somebody in that line of work?? Give me a reason to want him to live?? He's a killer. As they say in law enforcement, what goes around, comes around.? Now it's come around? to him.

If a protagonist isn't sympathetic, then he has to be compelling, fascinating,? The audience wants to watch what he does in spite of their default feelings about him.

That he's genetically engineered may be an? element on which to build a fascinating character with a compelling struggle.? But as is, it's almost a throw away in this logline.? What's the big dramatic deal about being genetically engineered?? What unique dramatic problem does it create for the character?? Which is to ask:? what's the story hook?

(A limited lifespan is already taken by the replicants in the "Blade Runner" wanna-be-franchise -- gotta come up with something different. And that he's being framed does not qualify as a? story hook because it's not a unique dramatic problem -- it's a rather common plot trope.)

fwiw

The guy's an assassin.? Why should I emphasize with his plight?? Why should I want to root for somebody in that line of work?? Give me a reason to want him to live?? He's a killer. As they say in law enforcement, what goes around, comes around.? Now it's come around? to him.

If a protagonist isn't sympathetic, then he has to be compelling, fascinating,? The audience wants to watch what he does in spite of their default feelings about him.

That he's genetically engineered may be an? element on which to build a fascinating character with a compelling struggle.? But as is, it's almost a throw away in this logline.? What's the big dramatic deal about being genetically engineered?? What unique dramatic problem does it create for the character?? Which is to ask:? what's the story hook?

(A limited lifespan is already taken by the replicants in the "Blade Runner" wanna-be-franchise -- gotta come up with something different. And that he's being framed does not qualify as a? story hook because it's not a unique dramatic problem -- it's a rather common plot trope.)

fwiw